Effects of time-dependent degradation and freezing on biomechanical properties of healthy bovine jejunum

ABSTRACT Degradation of bovine small intestine and respective effects on biomechanics have not been described to date. Biomechanical testing intestinal tissues is often carried out within a few hours donor death tissue deterioration accounted for. Freezing efficient for the preservation several tissues; however, it may cause cellular damage. This study investigated morphologic biomechanical changes jejunum at different postmortem moments. Effects freezing thawing morphology behavior were also examined. Macroscopic first noted eight death. At this time, histologic started set in, tests revealed lower bursting pressure (203.10±46.14mmHg). 12 hours, rearrangement was noted, increased (238.43±31.04mmHg). A second drop in detected 18 (235.20±38.21mmHg), followed by progressive until end experimental period. Histologic deterioration. Mechanical resistance did differ between thawed fresh specimens. It concluded that jejunal specimens retain up 6 after affect mechanical wall model.